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DNA-level editing of microbial communities for understanding and control.
Overview
  • Microbial communities are major contributors to the uptake and release of greenhouse gasses and are critical regulators of human health; however, efforts to precisely engineer their constituents' DNA are nascent. Our laboratory at the University of California, Berkeley brings DNA-editing tools to microbiomes.

  • In the short term, this approach should provide understanding of the interactions and unstudied organisms within communities.

  • Over the longer term, community editing offers a precise means for controlling microbiomes that are instrumental to our health, agriculture, climate, and industry.

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Media

August 27, 2023

Ben delves into ET-Seq and DART in this article about how we can harness precision microbiome editing to tackle climate change.

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The Lab

August 15, 2023

We are honored to announce funding by The Leona M. and Harry B. Helmsley Charitable Trust to UC Berkeley to support our efforts on microbiome editing as it applies to Crohn's disease!

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Social

August 9, 2023

Celebrating the first anniversary of the lab!

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Media

April 17, 2023

The Rubin Lab is excited to be part of IGI's new initiative for developing precision microbiome editing solutions, the recipient of $70M in funding from the Audacious Project.

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Diversity and Belonging

​​The Rubin Lab intentionally cultivates an inclusive, diverse, welcoming, and empathetic lab environment. We recognize that there are historical and institutional structures in science that marginalize under-represented communities. Accordingly, we strive to work consciously to dismantle these structures and foster a diverse community.

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